I am sorry for your loss. Yes, in the Personal Info section you would check the box stating that the person passed away and you would enter the date of passing. Then complete the tax return as normal using the tax forms received by person who passed, ie W-2's, Form 1099's etc. The program will automatically generate a Form 1310 for you. There are times when E-file may not work if the Social Security Administration has blocked the SSN already but you should be fine.

More information:

https://ttlc.intuit.com/replies/3300219