Get your taxes done using TurboTax

Well...In this case you are going to have to remove every entry for your spouse on this tax return.  All income from any source where he was listed as either receiving the income or jointly owned the income.  All deductions associated with him or jointly with him on the return.  All schedules where he was the owner or was jointly the owner.
Then after this you will have enter only your income and deductions.  Then go through the Review section where you will probably be shown multiple area's on the return that needs to be corrected because something was missed in the deletions of his information.

It would be easier and far more accurate for you to create a New account with a New user ID and start a new tax return with only your information with the MFS status.  On that return you only have to enter his name and Social Security number.  As stated in the following TurboTax support FAQ - "unless you already transferred info over from last year's joint return, in which case it's best to start over with a brand new return that has nothing transferred over"
See this TurboTax support FAQ for switching from filing as MFJ to MFS - <a rel="nofollow" target="_blank" href="https://ttlc.intuit.com/questions/2895311-how-do-i-switch-from-filing-jointly-to-filing-separately">...>

Also see this TurboTax support FAQ for filing jointly versus separately - <a rel="nofollow" target="_blank" href="https://ttlc.intuit.com/questions/1894449-is-it-better-for-a-married-couple-to-file-jointly-or-separ...>

And if you live in a community property state, that opens up another can of worms entirely when filing as Married Filing Separately - Community property states are: Arizona, California, Idaho, Louisiana, Nevada, New Mexico, Texas, Washington, and Wisconsin.
See this TurboTax support FAQ for Married Filing Separately in Community Property States - <a rel="nofollow" target="_blank" href="https://ttlc.intuit.com/questions/1901162-married-filing-separately-in-community-property-states">ht...>