Thanks for joining us today, lucasfelbel31!
Excellent question!
Congrats on branching out! You will not owe Social Security or Medicare taxes during the loss years.
For years that you project a profit, your Estimated Tax Payments will include the FICA.
Self-employment Tax Calculator
Here is an awesome link that goes into more detail: Self-employment Taxes
For additional helpful information: Estimated Taxes - Common Questions