Yes, unfortunately IRS Tax Topic 151 may delay your refund.
The message means that your federal tax return is under review for an unknown reason, and the IRS will be sending you a letter. The IRS generally asks for proof of income, deductions, or credits.
If you purchased Audit Defense, you should contact them first. If you don't contact them at the first notice, then they may not be able to assist you with the most beneficial outcome.
To read more about IRS Tax Topic 151 click the following link: IRS Tax Topic 151